发表论文 Publications

我们的科研成果与学术贡献 Our Research Outputs and Academic Contributions

2025
Shu-Guang Yang#, Chang-Ping Li#, Xue-Wei Wang#, Tao Huang#, Cheng Qian, Qiao Li, Ling-Rui Zhao, Si-Yu Zhou, Chen-Yun Ding, Rui Nie, Saijjilafu, Yu-Cai Hong*, Chang-Mei Liu*, Feng-Quan Zhou* (2025) Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration. Advanced Science. doi: 10.1002/advs.202405537

DOI: 10.1002/advs.202405537

2024
Cheng Qian#, Ying Xin#, Cheng Qi, Hui Wang, Bryan C Dong, Donald J Zack, Seth Blackshaw, Samer Hatter, Feng-Quan Zhou*, Qian J* (2024) Intercellular communication analysis identifies Oprm1 as a neuroprotective factor for retinal ganglion cells. Nature Communications. doi: 10.1038/s41467-024-46428-z

DOI: 10.1038/s41467-024-46428-z

Jing Zhang, Shu-Guang Yang*, Feng-Quan Zhou* (2024) Glycogen synthase kinase 3 signaling in neural regeneration in vivo. Journal of Molecular Cell Biology. doi: 10.1093/jmcb/mjad075

DOI: 10.1093/jmcb/mjad075

Yu Xia, Lu Ding, Changlin Zhang, Qi Xu, Ming Shi, Tianshun Gao, Feng-Quan Zhou*, David Y B Deng* (2024) Inflammatory Factor IL1α Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca2+/CaMK2b Pathway. Neuroscience Bulletin. doi: 10.1007/s12264-023-01128-4

DOI: 10.1007/s12264-023-01128-4

2023
Xue-Wei Wang#, Shu-Guang Yang#, Ming-Wen Hu#, Rui-Ying Wang#, Chi Zhang, Anish R Kosanam, Arinze J Ochuba, Jing-Jing Jiang, Ximei Luo, Yun Guan, Jiang Qian, Chang-Mei Liu*, Feng-Quan Zhou* (2023) Histone methyltransferase EZH2 coordinates mammalian axon regeneration via regulation of key regenerative pathways. Journal of Clinical Investigation. doi: 10.1172/JCI163145

DOI: 10.1172/JCI163145

Lu Ding, Weiwei Chu, Yu Xia, Ming Shi, Tian Li, Feng-Quan Zhou*, David Y B Deng* (2023) UCHL1 facilitates protein aggregates clearance to enhance neural stem cell activation in spinal cord injury. Cell Death and Disease. doi: 10.1038/s41419-023-06003-8

DOI: 10.1038/s41419-023-06003-8

Mei Zhang, Yong Zhang, Qian Xu, Joshua Crawford, Cheng Qian, Guo-Hua Wang, Jiang Qian, Xin-Zhong Dong, Mikhail V. Pletnikov, Chang-Mei Liu* & Feng-Quan Zhou* (2023) Neuronal Histone Methyltransferase EZH2 Regulates Neuronal Morphogenesis, Synaptic Plasticity, and Cognitive Behavior in Mice. Neuroscience Bulletin. doi: 10.1007/s12264-023-01074-1

DOI: 10.1007/s12264-023-01074-1

2022
Shu-Guang Yang, Xue-Wei Wang, Cheng Qian, Feng-Quan Zhou* (2022) Reprogramming neurons for regeneration: The fountain of youth. Progress in Neurobiology. doi: 10.1016/j.pneurobio.2022.102284

DOI: 10.1016/j.pneurobio.2022.102284

Qin Zheng, Wenrui Xie, Debora D Lückemeyer, Mark Lay, Xue-Wei Wang, Xintong Dong, Nathachit Limjunyawong, Yaqing Ye, Feng-Quan Zhou, Judith A Strong, Jun-Ming Zhang, Xinzhong Dong* (2022) Synchronized cluster firing, a distinct form of sensory neuron activation, drives spontaneous pain. Neuron. doi: 10.1016/j.neuron.2021.10.019

DOI: 10.1016/j.neuron.2021.10.019

2021
Qiao Li, Cheng Qian, Harry Feng, Tyger Lin, Qingsan Zhu, Ying Huang, Feng-Quan Zhou* (2021) N6-methyladenine DNA demethylase ALKBH1 regulates mammalian axon regeneration. Neuroscience Bulletin. doi: 10.1007/s12264-021-00671-2

DOI: 10.1007/s12264-021-00671-2

2020
Cheng Qian, Bryan Dong, Xu-Yang Wang, Feng-Quan Zhou* (2020) In vivo glial trans-differentiation for neuronal replacement and functional recovery in central nervous system. The FEBS Journal. doi: 10.1111/febs.15681

DOI: 10.1111/febs.15681

Shu-Guang Yang Chang-Ping Li, Xue-Qi Peng, Zhao-Qian Teng, Chang-Mei Liu*, Feng-Quan Zhou* (2020) Strategies to Promote Long-Distance Optic Nerve Regeneration. Frontiers in Cellular Neuroscience. doi: 10.3389/fncel.2020.00119

DOI: 10.3389/fncel.2020.00119

Cheng Qian, Feng-Quan Zhou* (2020) Updates and challenges of axon regeneration in the mammalian central nervous system. Journal of Molecular Cell Biology. doi: 10.1093/jmcb/mjaa026

DOI: 10.1093/jmcb/mjaa026

Fatima M Nathan, Yosuke Ohtake, Shuo Wang, Xinpei Jiang, Armin Sami, Hua Guo, Feng-Quan Zhou, Shuxin Li* (2020) Upregulating Lin28a Promotes Axon Regeneration in Adult Mice with Optic Nerve and Spinal Cord Injury. Molecular Therapy. doi: 10.1016/j.ymthe.2020.04.010

DOI: 10.1016/j.ymthe.2020.04.010

Xue-Wei Wang #, Shu-Guang Yang#, Chi Zhang#, ,Ming-Wen Hu, Jiang Qian, Jin-Jin Ma, Yingchi Zhang, Bin-Bin Yang, Yi-Lan Weng, Guo-Li Ming, Anish R. Kosanam, Saijilafu*, Feng-Quan Zhou* (2020) Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration. Cell Reports. doi: 10.1016/j.celrep.2020.107537

DOI: 10.1016/j.celrep.2020.107537

2018
Xue-Wei Wang, Qian Li, Chang-Mei Liu, Philip A Hall, Jing-Jing Jiang, Christopher D Katchis, Sehwa Kang, Bryan C Dong, Shuxin Li, Feng-Quan Zhou* (2018) Lin28 signaling supports mammalian PNS and CNS axon regeneration. Cell Reports. doi: 10.1016/j.celrep.2018.07.105

DOI: 10.1016/j.celrep.2018.07.105

2017
Kirill Gorshkov, Sohum Mehta, Santosh Ramamurthy, Gabriele V Ronnett, Feng-Quan Zhou, Jin Zhang* (2017) AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nature Chemical Biology. doi: 10.1038/nchembio.2298

DOI: 10.1038/nchembio.2298

Gang-Bin Tang, Yu-Qiang Zeng, Pei-Pei Liu, Ting-Wei Mi, Shuang-Feng Zhang, Shang-Kun Dai, Qing-Yuan Tang, Lin Yang, Ya-Jie Xu, Hai-Liang Yan, Hong-Zhen Du, Zhao-Qian Teng*, Feng-Quan Zhou*, Chang-Mei Liu* (2017) The histone H3K27 demethylase UTX regulates synaptic plasticity and cognitive behaviors in mice. Frontiers in Molecular Neuroscience. doi: 10.3389/fnmol.2017.00267

DOI: 10.3389/fnmol.2017.00267

2016
Yu Shin Kim, Michael Anderson, Kyoungsook Park, Qin Zheng, Amit Agarwal, Catherine Gong, Saijilafu, LeAnne Young, Shaoqiu He, Pamela Colleen LaVinka, Fengquan Zhou, Dwight Bergles, Menachem Hanani, Yun Guan, David C Spray, Xinzhong Dong* (2016) Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain. Neuron. doi: 10.1016/j.neuron.2016.07.044

DOI: 10.1016/j.neuron.2016.07.044

2015
J-J Jiang, C-M Liu, B-Y Zhang, X-W Wang, M Zhang, Saijilafu, S-R Zhang, P Hall, Y-W Hu, F-Q Zhou* (2015) MicroRNA-26a supports mammalian axon regeneration in vivo by suppressing GSK3β expression. Cell Death & Disease. doi: 10.1038/cddis.2015.239

DOI: 10.1038/cddis.2015.239

2014
Philip R Nicovich*, Feng-Quan Zhou* (2014) Acquisition frame rate affects microtubule plus-end tracking analysis. Nature Methods. doi: 10.1038/nmeth.2846

DOI: 10.1038/nmeth.2846

2013
Chang-Mei Liu, Rui-Ying Wang, Saijilafu, Zhong-Xian Jiao, Bo-Yin Zhang, Feng-Quan Zhou* (2013) MicroRNA-138 and Sirt1 form a mutual negative feedback loop to regulate axon regeneration. Genes & Development. doi: 10.1101/gad.209619.112

DOI: 10.1101/gad.209619.112

Saijilafu, Eun-Mi Hur, Chang-Mei Liu, Zhongxian Jiao, Wen-Lin Xu, Feng-Quan Zhou* (2013) PI3K-GSK3 pathway regulates mammalian axon regeneration by induction of Smad1. Nature Communications. doi: 10.1038/ncomms3690

DOI: 10.1038/ncomms3690

Saijilafu, Bo-Yin Zhang, Feng-Quan Zhou* (2013) Signaling pathways that regulate axon regeneration. Neuroscience Bulletin. doi: 10.1007/s12264-013-1357-4

DOI: 10.1007/s12264-013-1357-4

2011
Eun-Mi Hur, Saijilafu, Feng-Quan Zhou* (2011) Growing the growth cone: remodeling the cytoskeleton to promote axon regeneration. Trends in Neurosciences. doi: 10.1016/j.tins.2011.11.002

DOI: 10.1016/j.tins.2011.11.002

Saijilafu, Eun-Mi Hur, Feng-Quan Zhou* (2011) Genetic dissection of axon regeneration via in vivo electroporation of mouse adult sensory neurons. Nature Communications. doi: 10.1038/ncomms1568

DOI: 10.1038/ncomms1568

Eun-Mi Hur, Saijilafu, Byoung Dae Lee, Seong-Jin Kim, Wen-Lin Xu, Feng-Quan Zhou* (2011) GSK3 controls axon growth via CLASP-mediated regulation of growth cone microtubules. Genes & Development. doi: 10.1101/gad.17015911

DOI: 10.1101/gad.17015911

Eun-Mi Hur, In Hong Yang, Deok-Ho Kim, Justin Byun, Saijilafu, Wen-Lin Xu, Philip R Nicovich, Raymond Cheong, Andre Levchenko, Nitish Thakor, Feng-Quan Zhou* (2011) Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules. PNAS. doi: 10.1073/pnas.1011258108

DOI: 10.1073/pnas.1011258108

2010
Eun-Mi Hur, Feng-Quan Zhou* (2010) GSK3 signaling in neural development. Nature Reviews Neuroscience. doi: 10.1038/nrn2870

DOI: 10.1038/nrn2870

2006
Woo-Yang Kim, Feng-Quan Zhou, Jiang Zhou, Yukako Yokota, Yan-Min Wang, Takeshi Yoshimura, Kozo Kaibuchi, James R Woodgett, E S Anton, William D Snider* (2006) Essential roles for GSK-3s and GSK-3 primed substrates in neurotrophin-induced and hippocampal axon growth. Neuron. doi: 10.1016/j.neuron.2006.10.031

DOI: 10.1016/j.neuron.2006.10.031

Feng-Quan Zhou, Mark Walzer, Yao-Hong Wu, Jiang Zhou, Shoukat Dedhar, William D Snider* (2006) Neurotrophins support regenerative axon assembly over CSPGs by an ECM-integrin independent mechanism. Journal of Cell Science. doi: 10.1242/jcs.03016

DOI: 10.1242/jcs.03016

2005
Feng-Quan Zhou, William D Snider* (2005) GSK-3beta and microtubule assembly in axons. Science. doi: 10.1126/science.1110301

DOI: 10.1126/science.1110301

2004
Feng-Quan Zhou, Jiang Zhou, Shoukat Dedhar, Yao-Hong Wu, William D Snider* (2004) NGF-induced axon growth is mediated by localized inactivation of GSK-3β and functions of the microtubule plus end binding protein APC. Neuron. (Highlighted article with preview; a ‘Must read’ article by Facultyof1000) doi: 10.1016/j.neuron.2004.05.011

DOI: 10.1016/j.neuron.2004.05.011

2002
Feng-Quan Zhou, Clare M Waterman-Storer, Christopher S Cohan* (2002) Focal loss of actin bundles causes microtubule redistribution and growth cone turning. Journal of Cell Biology. (Cover image and highlighted article; a ‘must read’ article by Faculty of 1000) doi: 10.1083/jcb.200112014

DOI: 10.1083/jcb.200112014